Changes in Noninvasive Liver Fibrosis Indices and Spleen Size During Chemotherapy

Changes in Noninvasive Liver Fibrosis Indices and Spleen Size During Chemotherapy

Oxaliplatin-based regimens are standard treatments for the patients with colorectal cancer (CRC) and advanced gastric cancer (AGC). However, owing to hepatic sinusoidal obstruction syndrome (SOS), the use of oxaliplatin sometimes results in splenomegaly. The aim of the present study was to evaluate the correlation between chemotherapy-associated changes of noninvasive liver fibrosis indices and...

liver fibrosis and noninvasive serum based biomarkers

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noninvasive methods to evaluate liver fibrosis in chronic hcv infection

Noninvasive Measures of Liver Fibrosis and Severity of Liver Disease.

Determining the degree of fibrosis is an important step in the assessment of disease severity in patients with chronic liver disease. Liver biopsy has been the gold standard for estimating the extent of inflammation and fibrosis, although the procedure has limitations such as sampling error and variability. Noninvasive testing has been shown to be equally predictive in ruling out fibrosis or ru...

Assessment of Liver Fibrosis: Noninvasive Means

Liver biopsy, owing to its limitations and risks, is an imperfect gold standard for assessing the severity of the most frequent chronic liver diseases chronic hepatitis C (HCV), B (HBV) non alcoholic (NAFLD) and alcoholic (ALD) fatty liver diseases. This review summarizes the advantages and the limits of the available biomarkers of liver fibrosis. Among a total of 2,237 references, a total of 1...